Mellor Firsts were held 3-3 at home by Hazel Grove.
It was a disappointing result after Mellor defeated their local rivals 7-0 away.
Mellor had Matt Jamieson dismissed in the second half.
Craig Frisby, Matt Jamieson and Matt Cotton were Mellor's scorers.
Steve Smith was Man of the Match.
Mellor Seconds won 5-3 away at Rochdalians.
Mark Oldham (2), Ryan Yates, Luke Jubb and Carl Brindley were on target.
Tim Parker was Man of the Match.
The Thirds top the Division C table after a 5-3 win at home to title challenges Bury Amateur FC Reserves.
Sam Parker (2), Sam Healey, Pat Boyle and Rick Axford scored.
Sam Parker and Steve Baguley were jointly Man of the Match.
The Fourths went down 0-4 to Ashtonians away but it was an unfair reflection on the play.
Mellor lost keeper Phil Brown after 35 minutes to injury and missed a string of chances.
Clive Szmit was Man of the Match.